Marc Marquez made his 125cc World Championship debut in 2008 at the age of 15. He achieved his first podium at the British Grand Prix of that year making him the youngest Spanish rider to take a Grand Prix podium. His first win would come at Mugello in the 2010 season, the year he would go on to win the championship. For the 2011 season, Marquez moved into Moto2. He took his first win at the French Grand Prix, and he would go on to win six more races that season before an injury that caused vision problems hampered the end of the season for the Spaniard. Marquez continued in Moto2 for 2012 and had an incredible season. He won the championship with nine race wins and only finishing off the podium in three races. His performance in the 2012 Valencian Grand Prix has gone down in history for being one of the greatest comebacks as he started from 33rd on the grid and went on to win the race. 

Marquez moved into MotoGP for the 2013 season to race for the Repsol Honda Team. He started off strong with a podium in Qatar and took his first Grand Prix win at the second round of the season in America. Marquez fought it out for the championship against Jorge Lorenzo and in the final round of the season took the title to become the youngest champion in the series history. 2014 was another fantastic season for Marquez as he took 10 consecutive Grand Prix wins, becoming the third in history to achieve such a feat. Marquez would go on to win three more races and take the championship win. 2015 was not the season Marquez would have wanted, he started the season as the favourite for the championship once again, but he had several retirements throughout the season. With five race wins he was able to finish 3rd overall in the championship. Marquez had several stronger seasons in 2016, 2017, 2018, and 2019 where he would win the championship in each of these years. 2019 was his most dominant performance with 420 points and finishing in the top 2 podiums place in every race he finished in. Once the shortened 2020 season got underway in July, Marquez crashed out of the first race whilst chasing Fabio Quartararo for the win. In the crash he sustained a broken humerus in his right arm which would take him out of the 2020 season. Marquez made his return at the third round of the 2021 season and finished his first full race since the end of 2019 in 7th place. Marquez took his first race win in 581 days at the German Grand Prix. Marquez took two further wins in 2021 but was forced to sit out for the last two races to focus on rehabilitation. 2022 was off to a rocky start for Marquez. During the second round of the season, he had a violent high side crash and after being taken to hospital for checks he was diagnosed with Diplopia, the condition that hampered his 2011 Moto2 season. Marquez was side-lined for a large part of the 2022 season as he was opting to have a fourth surgery on his right arm at the Mayo Clinic in America. He returned to racing for the Aragon Grand Prix but was forced to retire due to two collisions with Fabio Quartararo and Takaaki Nakagami. At the Australian Grand Prix Marquez would take his 100th premier class podium. For the 2023 season, Marquez remains with the Repsol Honda Team.